Prenatal diagnosis of congenital cystic adenomatoid malformation of the lung by fetal lung biopsy

A case of type III congenital cystic adenomatoid malformation of the lung was successfully diagnosed prenatally by fetal lung biopsy. We performed this procedure at 22 weeks of gestation, using a biopsy gun system under ultrasound guidance. The pregnancy was undisturbed by the procedure but as the condition was incompatible with life, an abortion was performed. The diagnosis was confirmed at post-mortem examination. Fetal lung biopsy appears to be a useful method for prenatal diagnosis of fetal lung disorders.     

三峡工程与长江中游沿江产业带建设

讨论了长江中游沿江产业带发展条件、限制因素和未来发展，指出三峡工程的建设将对长江中游产业的布局和经济发展带来深刻的变化；防洪作用促进中游两岸大型工业项目的兴建，调整现有沿江城镇的布局，使之结构趋于合理化；电力供应经解能源的紧张状态，改善航运条件，发挥长江黄金水道的综合效益。当然，由于坝下河道冲刷，对现有的码头带来一定的影响，由于冬季水位抬升引起两岸低湖田地下水位上升，加剧两岸土壤潜育化和沼泽化。     

2002年3-6月国内安全事故数据

统计了2002年3-6月国内发生的各种安全事故871起,包括矿业事故、交通事故、爆炸事故、火灾、毒物泄露和中毒及其他事故.统计表明,在这些事故中,矿业事故最多,占61. 8%,平均每天4.5起事故,其次是交通事故(16.3%)、爆炸事故(6.7%)、火灾(6.0%)、其他事故(5.6%)、毒物泄露和中毒(3.7%).871起事故共死亡2 197人,伤3 321人,死亡人数的百分比分别为矿业事故53.7%、交通事故28.0%、火灾6.1%、爆炸事故5.9%、其他事故5.1%、泄露中毒1.2%;受伤人数的百分比分别为泄露中毒37.4%、交通事故26.9%、爆炸事故14.2%、矿业事故11.8%、其他事故5.3%、火灾4.4%.     

Exploring Chemical Variables in Ligustrum lucidum Ait. F. Tricolor (Rehd.) Rehd. in Relation to Air Pollutants and Environmental Conditions

Ligustrum lucidum Ait. f. tricolor (Rehd.) Rehd. in relation to atmospheric pollutants in Córdoba city, Argentina. The study area receives regional pollutants and was categorized taking into account traffic level, industrial density, type of industry, location of the sample point in relation to the street corner, treeless condition, and topographic level. Dried weight/fresh weight ratio (DW/FW) and specific leaf area (SLA) were calculated, and concentrations of chlorophylls, carotenoids, total sulfur, soluble proteins, malondialdehyde (MDA), and hydroperoxy conjugated dienes (HPCD) were determined in leaf samples. Sulfur content correlates positively with traffic density and SLA correlates negatively with some combinations of the categorical variables; MDA correlates positively with topographic level and total protein concentration correlates negatively with treeless condition. On the basis of our results, traffic, location of trees, type of industry, situation of a tree with respect to others, and topographic level are the environmental variables to bear in mind when selecting analogous sampling points in a passive monitoring program. An approximation to predict tree injury may be obtained by measuring DW/FW ratio, proteins, pigments, HPCD, and MDA as they are responsible for the major variability of data.     

治污投资的政府最优政策博弈

外部性的存在及制造商治污投资动机不足要求政府对制造商的行为进行相应的规制，政府在制造商的治污投资行为中主要的作用是通过各种措施使得制造裔有动机地去自觉地进行有效的治污投资;政府的主要控制手段包括直接管制及借助市场激励，政府制定环境管理策略的关键因素是“惩罚的力度与激励的强度”。基于社会福利最大化的角度；从制造商的治污投资行为出发研究政府制定环境管理规制的策略，通过一个三阶段的博弈模型分析福利增进量、洽污成本与治污效果等三个因素对“惩罚力度与激励强度”的影响。     

A comparison of different lysis buffers to assess allele dropout from single cells for preimplantation genetic diagnosis

Single cell polymerase chain reaction (PCR) for preimplantation genetic diagnosis (PGD) requires high efficiency and accuracy. Allele dropout (ADO), the random amplification failure of one of the two parental alleles, remains the most significant problem in PCR-based PGD testing since it can result in serious misdiagnosis for compound heterozygous or autosomal dominant conditions. A number of different strategies (including the use of lysis buffers to break down the cell and make the DNA accessible) have been employed to combat ADO with varying degrees of success, yet there is still no consensus among PGD centres over which lysis buffer should be used (ESHRE PGD Consortium, 1999 ). To address this issue, PCR amplification of three genes (CFTR, LAMA3 and PKP1) at different chromosomal loci was investigated. Single lymphocytes from individuals heterozygous for mutations within each of the three genes were collected and lysed in either alkaline lysis buffer (ALB) or proteinase K/SDS lysis buffer (PK). PCR amplification efficiencies were comparable between alkaline lysis and proteinase K lysis for PCR products spanning each of the three mutated loci (ΔF508 in CFTR 90% vs 88%; R650X in LAMA3 82% vs 78%; and Y71X in PKP1 91% vs 87%). While there was no appreciable difference between ADO rates between the two lysis buffers for the LAMA3 PCR product (25% vs 26%), there were significant differences in ADO rates between ALB and PK for the CFTR PCR product (0% vs 23%) and the PKP1 PCR product (8% vs 56%). Based on these results, we are currently using ALB in preference to PK/SDS buffer for the lysis of cells in clinical PGD. Copyright © 2001 John Wiley & Sons, Ltd.     

有意违章行为动因分析与控制对策探讨

对有意违章行为的含义进行了界定 ,并对有意违章行为产生的动因进行了详细分析 ,提出了有意违章行为的动因主要包含违章行为与遵章行为满足生理心理需要作用的差值ΔXW、违章行为会受到法规惩处的作用FW、违章行为可导致人身伤害的主观感觉的作用RW3个方面。同时对 3个方面的动因按弗鲁姆的激励理论进行了转化 ,给出了各自的含义说明。笔者按动因分析的结果 ,给出了控制有意违章行为的步骤和措施     

浮桥河水库浮游植物的多样性及其演变

1997年4月至1998年1月对浮桥河水库浮游植物状况进行了调查,结果表明:该水库常见浮游植物约189种,隶属于8门92属,其中硅藻门25属64种,绿藻门39属79种,蓝藻门17属30种,甲藻门、隐藻门、裸藻门、黄藻门及金藻门种类较少。其个体密度年平均为44.9×104ind/L;生物量年平均为6.439mg/L,其中蓝藻占33.37%,硅藻和绿藻分别占20.68%和20.16%,甲藻占16.31%。浮游植物现存量的季节变化表现为从春季开始平稳上升,至秋季达到最大值。蓝藻、硅藻、绿藻等主要种类的季节变化按生物量大小依次为:秋季夏季春季冬季。浮游植物现存量的水平分布为上游最高,中游次之,下游最低,库汊低于中游而略高于下游。群落的相似性表现为上、中游相近,下游和库汊相近。群落的物种多样性根据计算Shannon-Weiner指数为上游最大,其次为中游,下游再次,库汊最低。与1980年的调查结果相比较,浮桥河水库浮游植物种类小型化明显,生物量增加2.5倍。     

水资源条件约束下西北农村地区生态经济发展对策

西北地区生态脆弱，社会经济发展相对落后。农业在全区经济中占有重要的地位，所以农村地区可持续发展对于实现西北地区可持续发展具有重要意义。通过分析西北地区水资源现状及特点和本区农村社会、经济发展现状，认为西北地区水资源严重缺乏，干旱化趋势将长期存在；农业结构不合理，乡镇工业污染严重、城镇化进程缓慢是制约本区农村地区可持续发展的主要因素。在此基础上，提出了在水资源严重缺乏条件下西北农村地区实现生态经济可持续发展的具体对策：积极调整农业结构，大力发展节水农业和推进农业产业化；加强小城镇社区生态环境基础设施建设，实施城镇化发展战略和乡镇企业可持续发展；建设生态型的小城镇，建立农村地区新型生态能源结构，加强小流域综合治理是改善农村生态环境和实现农村地区生态经济可持续发展的有效途径。